Precautions and Interactions: Should be used with caution in individuals with bleeding disorders or those taking blood thinning medications such as aspirin or warfarin. Co administration of extracts of Carica papaya with oral hypoglycemic may lead to very low blood glucose as observed in one of the experimental animal study. Thus it is important to closely monitor the blood glucose levels regularly to avoid hypoglycemia.

Precautions and Interactions: Should be used with caution in individuals with bleeding disorders or those taking blood thinning medications such as aspirin or warfarin. Co administration of extracts of Carica papaya with oral hypoglycemic may lead to very low blood glucose as observed in one of the experimental animal study. Thus it is important to closely monitor the blood glucose levels regularly to avoid hypoglycemia. It has been found to increase the bioavailablity of amiodarone and therefore the dose should be adjusted accordingly when coadministered with carica papaya leaf extract. In vitro study demonstrated potentiating the action of various antibiotics like penicillin G , ampicillin, amoxyclav, cephalothin,polymyxin B, rifampicin, amikacin, nalidixic acid, gentamycin, cholarmphenicol, oflxacin when co administered with C.Papaya .The extract of C. papaya with antimicrobial agents possesses synergistic properties which act against the pathogenic organisms. Adverse effects: Nausea, Vomiting, Abdominal pain, Heartburn, Dyspepsia.

Precautions and Interactions: Should be used with caution in individuals with bleeding disorders or those taking blood thinning medications such as aspirin or warfarin. Co administration of extracts of Carica papaya with oral hypoglycemic may lead to very low blood glucose as observed in one of the experimental animal study. Thus it is important to closely monitor the blood glucose levels regularly to avoid hypoglycemia.